Forthcoming content

The following papers are just some of those published, submitted or scheduled to appear in Human Genomics Volume 3 :

• Influence of SLCO1B1 and CYP2C8 gene polymorphisms on rosiglitazone pharmacokinetics in healthy volunteers Christina L. Aquilante et al., Denver and Health Sciences Centre, School of Pharmacy, Department of Pharmaceutical Sciences, University of Colorado, USA
• A survey of genetic simulation software for population and epidemiological studies Michael E. Weale et al., Department of Medical and Molecular Genetics, King’s College London, UK
• Mitochondrial DNA sequence variation and neurodegeneration Michelangelo Mancuso et al. Department of Neuroscience, Neurological Clinic, University of Pisa, Italy
• A high incidence of polymorphic CYP2C19 variants in archival blood samples from Papua New Guinea Nuala. A. Helsby et al., Department of Molecular Medicine and Pathology, Auckland Cancer Society Research Centre, University of Auckland, New Zealand
• Update of the Olfactory Receptor Gene (OR) Superfamily  Daniel W. Nebert, Tsviya Olender, and Doron Lancet,University of Cincinnati Medical Centre, USA
• Hardy-Weinberg analysis of a large set of published association studies reveals genotyping error and a deficit of heterozygotes across multiple loci Srijan Sen, Pratima Naik and Margit Burmeister, Molecular & Behavioural Neuroscience Institute, University of Michigan, USA
• The role of aldehyde dehydrogenase-1 polymorphism in harmful alcohol consumption in a Finnish population' Penelope A Lindet al., Department of Genetic Epidemiology, Queensland Institute of Medical Research, Australia
• A comparison of programs for imputation of untyped SNPs using the HapMap as a reference Frank Dudbridge, Senior Statistician, MRC Biostatistics Unit, Institute of Public Health, UK
• Pharmacogenetics of the human beta-adrenergic receptor family and the ‘evolution’ of clinical practice Andrew W. Browne, Department of Developmental Biology, Children's Hospital Medical Centre, USA & Bryan Mitton, Department of Pediatrics, University of California, USA
• LIPE C-60G influences the effects of physical activity on body fat and plasma lipid concentrations: The Quebec Family Study Christophe Garenc et al.,  Department of Medicine, University of Laval, Québec, QC, Canada
• Orientation, distance, regulation and function of neighbouring genes Adrian Gherman, Ruihua Wang and Dimitrios Avramopoulos, John Hopkins University, School of Medicine, USA
• Genome-wide approaches to understanding human aging Matt Kaeberlein Department of Genome Sciences, University of Washington
• Pharmacogenomics of aldehyde dehydrogenase 5a1 (succinate semialdehyde dehydrogenase) and associated neurotoxicity of gamma-hydroxybutyrate K. Michael Gibson et al., Division of Medical Genetics, Departments of Paediatrics, Pathology and Human Genetics, School of Medicine and Graduate School of Public Health, University of Pittsburgh, USA
• Effect of the aldehyde dehydrogenase variant gene allele ALDH2*2 on blood acetaldehyde concentrations  Giia-Sheun Peng, Department of Neurology, Tri-Service General Hospital, Taiwan & Shih-Jiun Yin, Department of Biochemistry, National Defense Medical Centre, Taiwan
• Genome-wide identification of genetic determinants for the cytotoxicity of perifosine Wei Zhang et al., Section of Haematology & Oncology, Department of Medicine, University of Chicago, USA
• Book Review: ‘Biosimulation in Drug Development’ Michael P.H. Stumpf, Division of Molecular Biosciences, Centre for Bioinformatics, Imperial College London